1

Proposal

Scientific group /Principle investigator

GSI Liaison scientist

Title of the proposal

2

IBER_011_Rapp

GSI Darmstadt (DE) /Felicitas Rapp

Felicitas Rapp

The role of microglia and vascular damage in radiation-induced changes of the CNS

3

IBER_006_Patera

Foot collaboration (IT) /Vincenzo Patera

Uli Weber

FOOT@SPACE

4

IBER_010_LaTessa

University of Trento and TIFPA (IT) / Chiara La Tessa

Uli weber

Measurements of neutron production in thick passive shielding and assessment of LET distributions for shielding and      assessment of LET distributions for radiobiological effects

5

IBER_007_Iliakis

University of Duisburg-Essen (DE) /George Iliakis

Micheal Scholz

Analysis of DNA double-strand-break-forms induced by space radiation and definition of their processing requirements for optimizing radiation protection

6

IBER_005_Hellweg

erman Aerospace Center DLR (DE) /Christine E. Hellweg

Insa Schröder

Mechanisms of heavy ion-induced damage in primary neuronal cells (NEURON)

7

IBER_008_Thielemann

Univ. of Applied Sciences Aschaffenburg (DE) /Christiane Thielemann

Sylvia Ritter

Human induced pluripotent stem cell derived in vitro models for space radiation biology - iRAD

8

IBER_009_Hespeels

Laboratory of Evolutionary Genetics and Ecology (LEGE), Namur (BE) / B. Hespeels

Sylvia Ritter

“Breaking bad?” Genomic evolution and protective mechanisms in asexual bdelloid rotifers exposed to charged particle beams

9

IBER_002_Moreels

SCK•CEN Radiobiology, Boeretang (BE) /M. Moreels

Burkhard Jakob

Stability of Medicines After exposure to particle RadiaTion (SMART)

10

IBER_001_Thiel

TU Darmstadt (DE) /Gerhard Thiel

Claudia Fournier

The effect of ionizing irradiation on the function of two cardiac ion channels in the context of a risk of sudden heart failure

11

IBER_004_Averbeck

GSI Darmstadt (DE) /Nicole Averbeck

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Study on the molecular mechanism of break-end resection, a step in repair of heavy¬ion induced DNA-double-strand breaks suggested to be involved in cancer induction

12

IBER_003_Manda

Victor Babes” National Institute of Pathology, Bucharest (RO) /Gina Manda

Nicole Averbeck

Redox signalling and the transcription factor NRF2 as therapeutic target for counteracting the deleterious effects of spaceflight environment (ABEL-IBER 2017)