GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt operates one of the leading particle accelerators for science. In the next few years, the new FAIR (Facility for Antiproton and Ion Research) one of the world's largest research projects, will be built in international cooperation. GSI and FAIR offer the opportunity to work together in this international environment with a team of employees committed to ensuring each day to conduct world-class science.

The Biophysics department is an interdisciplinary collaboration of biologists, physicists, chemists, biochemists and technicians. We are looking for as soon as possible a

PhD candidate part-time 65% (all genders)

Posting-ID: 25.37-1560

to do research in the group Immune system and tissue radiobiology in the research field of immunotherapy in combination with radiotherapy.

Topic of the thesis: The work will be related to immunological processes of tumors following irradiation. Combinations of radiation with immunotherapies (e.g. RNA vaccines and checkpoint inhibitors) will be explored. In particular, the difference in the immunogenic response for conventional photon therapy and carbon ion radiotherapy will be investigated.

Your tasks:

• Develop and implement novel radiobiological methods, including murine models
• Design and execution of irradiation experiments devoted to in vitro and in vivo radiobology and immunology research, particularly experiments linked to our collaboration partners working with mRNA vaccines
• Analysis of experimental datasets
• Involvement in scientific publications and dissemination of project results

Requirements:

• Master degree (or comparable) in Immunology, Biology, Biotechnology or a related disciplines
• Strong interest in tumor immune biology and tumor radiotherapy
• Knowledge in the field of immunology and/or radiobiology as well as cell and molecular biology, including state-of-the-art methods
• Interest and knowledge of bioinformatics and omics technologies is a plus
• Fairly good English language skills and enjoying work in an international environment
• Excellent ability to work in a team and a high degree of flexibility as well as autonomy
• Experience in design, conduction and analysis of complex experiments
• Certificate for animal experimentation (FELASA B) is a plus
• Pro-active, creative, enthusiastic and result-driven mindset

We offer an interesting position in an innovative, interdisciplinary and well-equipped research department, world leading in biophysics and radiation biology research with charged particle beams.

The position is limited to 3 years for a PhD candidate with the salary and benefits based on the Collective Agreement for the German Public Service (TVöD-Bund) effective at GSI. The candidate is admitted to the HGS Hire graduate school.

GSI supports the vocational development of women. Therefore, women are especially encouraged to apply for the position.

Handicapped persons will be preferentially considered when equally qualified.

Information about FAIR and GSI is available at www.gsi.de and www.fair-center.eu.

Inquiries concerning the position can be sent to Prof. Dr. Claudia Fournier or Dr. Alexander Helm (Mail: c.fournier(at)gsi.de, a.helm(at)gsi.de).

If you are interested in working in an exceptional international, highly technical environment, please send your complete application documents and details of your earliest possible starting date, quoting the Posting-ID: 25.37-1560 by 25.04.2025 at the latest via the online portal on our job site:

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GSI Helmholtzzentrum für Schwerionenforschung GmbH

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