particular shielding of space vessels and habitats, thus called SpaceTRiP. Just as in radiotherapy, the target geometry is described by regular cubic voxels, but with different material composition. The internal [...] meet additional requirements, i.e. projectiles up to iron, energies up to 1 GeV/n and above, various target materials etc. Microscopic Monte Carlo calculations On the microscopic/nanoscopic scale one has to [...] of the prechemical and chemical stage of radiation interaction in pure or oxygenated [8] water targets. This new functionality is being applied to investigate radiosensitization by nanoparticles, the